Each poppers contains one or more of the following ingredients mixed together:
- isopropyl nitrite (WE:208-779-0, CAS: 541-42-4)
- Pentyl nitrite (WE: 207-332-7, CAS: 463-04-7)
- isopropanol (WE: 200-661-7, CAS: 67-63-0)
and additives:
- Di-Sec Butylcarbinol
- 1-Pentanol
- aromas

In 2007, Regulation (EC) No 1907/2006 of the European Parliament and of the Council of 18 December 2006 came into force, which, inter alia, prohibited the sale to consumers (private individuals) of preparations containing isobutyl nitrite (Index No 007-017-00-2, EC 208-819-7, CAS 542-56-3). In Poland, an identical ban has been in force since 24 August 2007 on the basis of the Regulation of the Minister of Economy on restrictions, bans or conditions on the production, marketing or use of hazardous substances and preparations and products containing them (Journal of Laws 06.239.1731). Practice has shown that, from the very beginning, the ban has been strictly adhered to by all manufacturers and sellers and there are no poppers containing isobutyl nitrite on the market, including the long-popular original Rush poppers.